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What is Guillain-Barre Syndrome? Everything we know about the rare autoimmune disorder 

The symptoms of GBS can develop rapidly. As the immune system attacks peripheral nerves, victims typically experience a loss of feeling that gradually spreads throughout the body.

“​​Weakness and tingling in your extremities are usually the first symptoms,” the Mayo Clinic says. “These sensations can quickly spread, eventually paralyzing your whole body. In its most severe form Guillain-Barre syndrome is a medical emergency. Most people with the condition must be hospitalized to receive treatment.”

In severe cases, muscles affecting speech, swallowing, and breathing may be paralysed. In about 20 to 30 per cent of cases, GBS can lead to respiratory failure, and between 4 and 7 per cent of patients die.

On the other hand, most people with GBS do recover, the Mayo Clinic says, and 60- to 80 per cent are able to walk again after six months.

What causes Guillain-Barre Syndrome?

The causes of GBS are mysterious. Scientists don’t know why people develop the syndrome, but it often begins not long after an infection of some kind.

“The exact cause of Guillain-Barre syndrome isn’t known,” the Mayo Clinic says. “The disorder usually appears days or weeks after a respiratory or digestive tract infection.”

One theory is that GBS is triggered by the immune system’s overreaction to a bacterial or viral infection.

How common is it?

Thankfully, Guillain-Barre syndrome is rare. In Europe and North America, it affects only one to two members of the general public out of 100,000 each year.

Is GBS caused by the Johnson & Johnson vaccine?

In very rare cases, recipients of the Johnson & Johnson (also called “Janssen”) vaccine for Covid-19 have developed Guillain-Barre Syndrome, but experts say there is not enough data to indicate that one causes the other.

Out of 12.8 million people who have received the shot, only about 100 are suspected to have developed GBS afterward. Nevertheless, the US Food and Drug Administration issued a warning to Johnson & Johnson recipients regarding the syndrome – but emphasised that the risk was extremely small, especially compared to the dangers of getting Covid.

“Although the available evidence suggests an association between the Janssen vaccine and increased risk of GBS, it is insufficient to establish a causal relationship,” the FDA said in a statement. “Importantly, the FDA has evaluated the available information for the Janssen COVID-19 Vaccine and continues to find the known and potential benefits clearly outweigh the known and potential risks.”

In the case of Ms Jameson, the actress says her GBS was definitely not caused by a vaccine.

“PS I did NOT get the jab or any jab,” Ms Jameson wrote in her Instagram post. “This is NOT a reaction to the jab. Thank you for your concern.” 

Reference: Independent: Nathan Place